How It Works
Nitrazepam increases the effect of GABA, a neurotransmitter that reduces brain activity. This calming action supports sleep and helps control abnormal nerve signals. As a result, it promotes sleep onset and improves overall sleep quality.
Dosage
Adults usually take 5–10 mg at bedtime, while elderly or weakened patients begin with 2.5–5 mg. Dose and duration must be determined by a doctor to lower dependence risk. Treatment should remain short-term to prevent dependency.
Side Effects
Common side effects include sleepiness, dizziness, tiredness, and impaired coordination. Incorrect or prolonged use may lead to dependence, confusion, or memory issues. Long-term or excessive doses raise the risk of tolerance and dependence.
Pregnancy & Breastfeeding
Not recommended during pregnancy, particularly in the first trimester, due to potential fetal harm. Nitrazepam is excreted in breast milk, therefore breastfeeding is not advised. Use in late pregnancy may cause withdrawal symptoms in newborns.
Storage
Store below 25°C in a dry, cool place protected from direct light. Keep the medicine in its original pack to avoid moisture exposure. Always keep it out of children’s reach.
UK Regulation
Nitrazepam is classified as a Prescription Only Medicine (POM) in the UK. It is listed as a Class C controlled drug under the Misuse of Drugs Act. Legal supply and use require a valid medical prescription.